A case of Cushing's syndrome in an infant.

The patient, a girl, was born after a normal full-term pregnancy. Her birth weight was 8 lb. 4 oz. (75th percentile) and at 12 months, when she was apparently normal, her weight was 24 lb (75th percentile). Two months later she was brought to hospital because of her rapid gain in weight and increasing irritability. During this period she had gained 4 lb. 14 oz. and weighed 28 lb. 14 oz. (97th percentile). Thus the onset of her condition was short and dramatic (Figs. 1 and 2). On examination (Fig. 2) she was obese, with a buffalo hump, her face was plethoric and she had an acneiform rash. There was slight hirsutes of the face and back. No striae were present. She had a small umbilical